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There is a close correlation between treatment with calcitriol and the development of hypercalcaemia.
The treatment of acute accidental overdosage of Rocaltrolcalcitriolshould consist of general supportive measuresIf drug ingestion is discovered within a relatively short timeinduction of emesis or gastric lavage may be of benefit in preventing further absorptionIf the drug has passed through the stomachthe administration of mineral oil may promote its fecal eliminationSerial serum electrolyte determinationsespecially calciumrate of urinary calcium excretionand assessment of electrocardiographic abnormalities due to hypercalcemia should be obtainedSuch monitoring is critical in patients receiving digitalisDiscontinuation of supplemental calcium and a low-calcium diet are also indicated in accidental overdosageDue to the relatively short duration of the pharmacological action of calcitriolfurther measures are probably unnecessaryShouldhoweverpersistent and markedly elevated serum calcium levels occurthere are a variety of therapeutic alternatives which may be considereddepending on the patient’s underlying condition.
An abrupt increase in calcium intake as a result of changes in diete.gincreased consumption of dairy productsor uncontrolled intake of calcium preparations may trigger hypercalcaemiaPatients and their families should be advised that strict adherence to the prescribed diet is mandatory and they should be instructed on how to recognise the symptoms of hypercalcaemia.
Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.
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