In some embodiments, the serpina-1 polypeptide and or albumin polypeptide is measured using a protein chip assay.
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SAPALDIA study design for the determination of AAT associated genetic variantsa consisting of subjects with abnormally low AAT levels independent of PI S or Z allelessee Materials and Methods
It should be noted that whilein theorytwo different sequences could have the same checksum valuethe likelihood that this would happen is extremely low.
AffiliationsSchool of Population HealthUniversity of Western AustraliaPerthAustraliaPathology and Laboratory MedicineUniversity of Western AustraliaPerthAustraliaBusselton Population Medical Research FoundationPerthAustralia.
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it is caused by inheritance of two severe deficiency alleles of the serpina-1 gene located on chromosome segment 14q31 32.