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Tykerb is used together with another medicine called capecitabine xeloda or letrozole femara to treat a certain type of advanced breast cancer that. Timberland FR

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Exposure of an unborn child to this medication could cause birth defectsso you should not become pregnant while on this medicationEffective birth control is necessary during treatment if your menopause status has not been confirmedYou should not breastfeed while receiving this medication.

In harmonising the contraindicationsthe CHMP decided against including two contraindications that were in the SmPCs of some EU countriesliver impairment and pre-operative use in patients whose receptor status is negative or unknownThe CHMP was of the view that it was more appropriate to include relevant warnings in section 4.4.

In women who have gone through menopauseestrogen is mainly produced by converting androgenssex hormones produced by the adrenal glandsinto estrogensWhile estrogen may not actually cause breast cancerit is a necessary hormone for the cancer cells to grow in estrogen receptor-positive breast cancersWith estrogen blockedthe cancer cells that feed off estrogen may not be able to survive.

Fatigue is very common during cancer treatment and is an overwhelming feeling of exhaustion that is not usually relieved by restWhile on cancer treatmentand for a period afteryou may need to adjust your schedule to manage fatiguePlan times to rest during the day and conserve energy for more important activitiesExercise can help combat fatiguea simple daily walk with a friend can helpTalk to your healthcare team for helpful tips on dealing with this side effect.

The CHMPin light of the data submitted and the scientific discussion within the Committeewas of the opinion that the SmPCslabelling and package leaflets should be harmonised across the EU.

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