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Before using this medicationtell your doctor or pharmacist your medical historyespecially ofblood circulation problemsfor examplein your legsarms/handsor stomachcertain types of headacheshemiplegic or basilar migraineheart problemssuch as chest painirregular heartbeatprevious heart attackliver diseaseseizurestroke ormini-stroketransient ischemic attack
Serotonin syndromeincluding altered mental statusautonomic instability and neuromuscular abnormalitieshas been reported following concomitant treatment with triptans and selective serotonin reuptake inhibitorsSSRIsor serotonin noradrenaline reuptake inhibitorsSNRIsThese reactions can be severeIf concomitant treatment with rizatriptan and an SSRI or SNRI is clinically warrantedappropriate observation of the patient is advisedparticularly during treatment initiationwith dose increasesor with addition of another serotonergic medicationsee section 4.5
Feeling of pain or tightness in your jawneckor throatchest pain or heavy feelingpain spreading to the arm or shouldernauseasweatinggeneral ill feelingsudden numbness or weaknessespecially on one side of the bodysudden severe headacheconfusionproblems with visionspeechor balancesudden and severe stomach pain and bloody diarrheanumbness or tingling and a pale or blue-colored appearance in your fingers or toesorif you are also taking an antidepressantagitationhallucinationsfeverfast heart rateoveractive reflexesnauseavomitingdiarrhealoss of coordinationfainting.
Patients taking propranololLimit dose to 5 mg PO and do not exceed 15 mg/24 hr.
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