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Contraindications and precautions Contraindicated in patients hypersensitive to drug and patients with anuriahepatic comaor severe electrolyte depletionContraindicated if increased azotemiaoliguriaor progressive renal disease occur during therapyUse cautiously in pregnant womenpatients with sulfa allergyand in those with hepatic cirrhosis.

Individual intolerance to the active ingredient or other components of the medication dehydration hypokalemia and/or hyponatremialow potassium and/or sodium content in the bloodfailure of renal function comatose or precomatose condition due to hepatic encephalopathy pregnancy breastfeeding.

Furosemide is primarily used for the treatment of hypertension and edemaIt is the first-line agent in most people with edema caused by congestive heart failureIt is also used for hepatic cirrhosisrenal impairmentnephrotic syndromein adjunct therapy for cerebral or pulmonary edema where rapid diuresis is requiredIV injectionand in the management of severe hypercalcemia in combination with adequate rehydration.

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