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Metaxalone should be administered with great care to patients with pre-existing liver damageSerial liver function studies should be performed in these patients.

Metaxalone should be administered with great care to patients with pre-existing liver damageSerial liver function studies should be performed in these patients.

Check the labels on all your medicinessuch as allergy or cough-and-cold productsbecause they may contain ingredients that cause drowsinessAsk your pharmacist about using those products safely.

Other drugs may interact with metaxaloneincluding prescription and over-the-counter medicinesvitaminsand herbal productsTell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Increased risk of sedationrespiratory depression with concomitant other CNS depressantsegalcoholbenzodiazepinesopioidsTCAsmonitor closelyRisk of serotonin syndrome with serotonergic drugsegSSRIsSNRIsTCAstriptans5-HT 3 antagonistsopioidsmirtazapinetrazodonetramadolMAOIslinezolidIV methylene bluemonitor and discontinue if suspectedConcomitant with food may enhance CNS depressionMay cause falseBenedict’s test.

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skelaxin has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber.

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